Developing glyphosate resistant transgenic crop plants using class-1 EPSP synthase

Glyphosate is broad-spectrum systemic herbicide that strongly inhibit class-1 EPSP synthase an important enzyme involved in aromatic amino acid synthesis in plants

Quality: the transgenic crops are not only herbicide tolerance but also enhance yield
Enhanced efficacy: No crop injury even at high dose of glyphosate
Cost advantage: More efficient alternate to the existing technology
Shelf life: Transgenic crops can be propagated forever
Ease of use: Like any other crop seeds

Direct use to farmers for weed control in the agriculture. Agri-Biotech companies for developing transgenic crops for weed management

The class-1 EPSP synthase present in crop plants is very sensitive to the herbicide glyphosate, currently the glyphosate resistant class-II EPSP synthase encoding gene from pathogenic Agrobacterium CP4 bacterial strain was used for transgenic overexpression in crop plants for glyphosate tolerance. We engineered glyphosate resistant Class-I EPSP synthase encoding gene whose overexpression has several advantages in addition to the glyphosate tolerance

Indian Patent application No 202511009070